Für Ärzte/Ärztinnen

Hier gibt es Unterstützung für die Betreuung Ihrer Reizdarm-Patienten:


Ein SIBO-Atemtest sollte Ihnen und Ihren Patienten individuelle und differenzierte Testergebnisse liefern, gemäß aktuellster wissenschaftlicher Erkenntnisse und unter Einbeziehung der Expertise international führender SIBO-Ärzte!


Ergänzende Links zu Studien und anderen Dokumenten:

 

REIZDARM

 

Changes in Fecal Calprotectin After Rifaximin Treatment in Patients With Nonconstipated Irritable Bowel Syndrome (IBS).

https://www.ncbi.nlm.nih.gov/pubmed/30611316

 

A randomized double-blind placebo-controlled trial showing rifaximin to improve constipation by reducing methane production and accelerating colon transit: A pilot study.

https://www.ncbi.nlm.nih.gov/pubmed/30406392

 

Launch of ibs-smart™, an advancement in blood testing for Irritable Bowel Syndrome (IBS) 

https://www.prnewswire.com/news-releases/launch-of-ibs-smart-an-advancement-in-blood-testing-for-irritable-bowel-syndrome-ibs-announced-by-gemelli-biotech-in-partnership-with-the-medically-associated-science-and-technology-program-mast-at-cedars-sinai-300728775.html

 

Assessment of Anti-vinculin and Anti-cytolethal Distending Toxin B Antibodies in Subtypes of Irritable Bowel Syndrome.

https://www.ncbi.nlm.nih.gov/pubmed/28451914

 

Cedars-Sinai Research Identifies Gut Gas Linked to Diarrhea (Hydrogen Sulfide)

https://www.cedars-sinai.org/newsroom/cedars-sinai-research-identifies-gut-gas-linked-to-diarrhea/

 

Review of rifaximin as treatment for SIBO and IBS

https://www.ncbi.nlm.nih.gov/pubmed/19243285

 

Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

https://www.ncbi.nlm.nih.gov/pubmed/29508268

 

Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949258/

 

Update on Irritable Bowel Syndrome Diagnostics and Therapeutics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969781/

 

IBSchek - The First Clinically Validated Blood Test for IBS with Predominant Diarrhea (IBS-D) and Mixed Symptoms (IBS-M)

http://www.commdx.com/irritable-bowel-syndrome.html

 

Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome

https://www.ncbi.nlm.nih.gov/pubmed/11151884/

 

25 % aller Nicht-Antibiotika schädigen Darmbakterien

https://www.ernaehrungsmedizin.blog/2018/03/20/hunderte-medikamente-schaedigen-darmbakterien/

 

Proton pump inhibitors (PPI) therapy and risk of C. diff. infection: Systematic review and meta-analysis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643276/

 

FODMAP

 

Kluyveromyces marxianus-Hefe ermöglicht die Herstellung von FODMAP-armem Vollkornbrot

https://www.ncbi.nlm.nih.gov/pubmed/30166134

 

Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs

https://www.ncbi.nlm.nih.gov/pubmed/28740352

 

Diet in irritable bowel syndrome: What to recommend, not what to forbid to patients!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467063/

 

Efficacy of the low FODMAP diet for treating irritable bowel syndrome: the evidence to date

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918736/

 

A diet low in FODMAPs reduces symptoms of irritable bowel syndrome

https://www.ncbi.nlm.nih.gov/pubmed/24076059

 

Comparison of symptom response following advice for a diet low in fermentable carbohydrates (FODMAPs) versus standard dietary advice in patients with irritable bowel syndrome

https://www.ncbi.nlm.nih.gov/pubmed/21615553

SIBO

 

A randomized double-blind placebo-controlled trial showing rifaximin to improve constipation by reducing methane production and accelerating colon transit: A pilot study.

https://www.ncbi.nlm.nih.gov/pubmed/30406392

 

Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth.

https://www.ncbi.nlm.nih.gov/pubmed/29508268

 

Rifaximin Therapy for Patients with Irritable Bowel Syndrome without Constipation

https://www.ncbi.nlm.nih.gov/pubmed/21208106

 

Treatment of SIBO

http://www.townsendletter.com/FebMarch2015/sibo0215_2.html 

 

Irritable bowel syndrome and small intestinal bacterial overgrowth: Meaningful association or unnecessary hype

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949258/

 

How to Test and Treat Small Intestinal Bacterial Overgrowth: an Evidence-Based Approach

https://www.ncbi.nlm.nih.gov/pubmed/26780631

 

Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome

https://www.ncbi.nlm.nih.gov/pubmed/11151884/

 

Review of rifaximin as treatment for SIBO and IBS

https://www.ncbi.nlm.nih.gov/pubmed/19243285

 

Eubiotic properties of rifaximin: Disruption of the traditional concepts in gut microbiota modulation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504364/

 

Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system.

https://www.ncbi.nlm.nih.gov/pubmed/20852272

 

A 14-day elemental diet is highly effective in normalizing the lactulose breath test

https://www.ncbi.nlm.nih.gov/pubmed/14992438

 

Estimating the contribution of acute gastroenteritis to the overall prevalence of irritable bowel syndrome

https://www.ncbi.nlm.nih.gov/pubmed/22523730

 

Two Independent Networks of Interstitial Cells of Cajal Work Cooperatively with the Enteric Nervous System to Create Colonic Motor Patterns

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153851/

 

Update on Irritable Bowel Syndrome Diagnostics and Therapeutics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969781/

 

Clinical trial: the combination of rifaximin with partially hydrolysed guar gum is more effective than rifaximin alone in eradicating small intestinal bacterial overgrowth.

https://www.ncbi.nlm.nih.gov/pubmed/20937045

 

Influence of Saccharomyces boulardii CNCM I-745on the gut-associated immune system (also known as Saccharomyces cerevisiae HANSEN CBS 5926)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027949/

Download
ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth SIBO 2020
ACG_Clinical_Guideline__Small_Intestinal
Adobe Acrobat Dokument 406.0 KB
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Repeat Rifaximin for Irritable Bowel Syndrome: No Clinically Significant Changes in Stool Microbial Antibiotic Sensitivity
Repeat Rifaximin.pdf
Adobe Acrobat Dokument 258.8 KB
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Hydrogen and Methane-Based Breath Testing in Gastrointestinal Disorders: The North American Consensus
Breath Testing - North American Consensu
Adobe Acrobat Dokument 223.5 KB
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Systematic review with meta-analysis: rifaximin is effective and safe for the treatment of small intestine bacterial overgrowth
Rifaximin.pdf
Adobe Acrobat Dokument 387.3 KB
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A Combination of Rifaximin and Neomycin Is Most Effective in Treating Irritable Bowel Syndrome Patients With Methane on Lactulose Breath Test
Rifaximin - Neomycin.pdf
Adobe Acrobat Dokument 132.1 KB
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Herbal Therapy Is Equivalent to Rifaximin for the Treatment of Small Intestinal Bacterial Overgrowth
Herbal Antibiotics - Rifaximin.pdf
Adobe Acrobat Dokument 1.0 MB
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A 14-Day Elemental Diet Is Highly Effective in Normalizing the Lactulose Breath Test
Elemental Diet.pdf
Adobe Acrobat Dokument 156.2 KB
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Low-Dose Nocturnal Tegaserod or Erythromycin Delays Symptom Recurrence After Treatment of Irritable Bowel Syndrome Based on Presumed Bacterial Overgrowth
Prokinetics for SIBO.pdf
Adobe Acrobat Dokument 290.6 KB
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Low Dose Naltrexone: Side Effects and Efficacy in Gastrointestinal Disorders
Prokinetic LDN.pdf
Adobe Acrobat Dokument 4.1 MB
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Systematic Review: Cardiovascular Safety Profile of 5-HT4 Agonists Developed for Gastrointestinal Disorders
Prokinetic Prucalopride.pdf
Adobe Acrobat Dokument 267.4 KB
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Dr. Siebeckers Behandlungsschema (Mai 2018)
Siebeckers-Behandlungsschema-05-05-18_de
Adobe Acrobat Dokument 2.4 MB
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Dr. Siebeckers Vorschläge zur Symptomlinderung
Siebecker_sibo_symptomatic_relief_sugges
Adobe Acrobat Dokument 197.6 KB

METHANOGENE

 

Methanobrevibacter smithii is the predominant methanogen in patients with constipation-predominant IBS and methane on breath

https://www.ncbi.nlm.nih.gov/pubmed/22573345

 

Lovastatin lactone may improve irritable bowel syndrome with constipation (IBS-C) by inhibiting enzymes in the archaeal methanogenesis pathway

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909102/

Download
A new term for methanogens rather than SIBO: Intestinal Methanogen Overgrowth (IMO)
ACG_Clinical_Guideline__Small_Intestinal
Adobe Acrobat Dokument 406.0 KB

HYDROGENSULFID   (Flat-Line Test Results / "Non-Responder")

 

Hydrogen Sulfide Dysbiosis: A Case Study ("Flat Line" Breath Test Result)

https://ndnr.com/gastrointestinal/hydrogen-sulfide-dysbiosis-a-case-study/

 

Hydrogen sulphide in exhaled breath: a potential biomarker for small intestinal bacterial overgrowth in IBS.

https://www.ncbi.nlm.nih.gov/pubmed/27163246

 

Cedars-Sinai Research Identifies Gut Gas Linked to Diarrhea (Hydrogen Sulfide)

https://www.cedars-sinai.org/newsroom/cedars-sinai-research-identifies-gut-gas-linked-to-diarrhea/

 

Download
Phenotype and Antibiotic Response in Patients With Flat Line Breath Test Results: A Large Scale Database Analysis
Flat Line Breath Test Result.pdf
Adobe Acrobat Dokument 633.9 KB

SIFO (Small Intestinal Fungal Overgrowth)

 

Download
SIFO - A Cause of Gastrointestinal Symptoms (AGA Gastroenterology)
SIFO - A Cause of Gastrointestinal Sympt
Adobe Acrobat Dokument 693.1 KB

BIOFILM

 

Biofilm formation of mucosa-associated methanoarchaeal strains

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086402/

 

Biofilms: What Have We Learned from the Research?

http://ndnr.com/gastrointestinal/biofilms-what-have-we-learned-from-the-research/

 

Candida Biofilms: Threats, Challenges, and Promising Strategies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816785/

 

Candida glabrata Biofilms: How Far Have We Come?

https://www.mdpi.com/2309-608X/3/1/11/htm

Download
Discussion about the issues surrounding biofilm therapies, Discussion of the safe uses of biofilm Tx with Rx
Dr Anderson re Biofilm-05-31-2016.pdf
Adobe Acrobat Dokument 207.0 KB

CANDIDA

 

Candida Biofilms: Threats, Challenges, and Promising Strategies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816785/

 

Plants’ Natural Products as Alternative Promising Anti-Candida Drugs

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628516/

 

Candida glabrata Biofilms: How Far Have We Come?

https://www.mdpi.com/2309-608X/3/1/11/htm

MCAS (Mastcell Activation Syndrome)

 

What is Mast Cell Activation Syndrome (MCAS)?

https://www.drtaniadempsey.com/mastcellactivationsyndrome

 

Ein Webinar von Dr. Afrin (in Englisch) zum Thema MCAS gibt es am Seitenende der folgenden Website:

https://www.drtaniadempsey.com/aboutdrafrin

 

Characterization of Mast Cell Activation Syndrome

https://www.ncbi.nlm.nih.gov/pubmed/28262205

 

Meilenstein in der Diagnostik von Mastzellerkrankungen

https://www.ukb.uni-bonn.de/42256BC8002AF3E7/vwWebPagesByID/27D4C009920E64E6C12571FD003AF0D8

 

Fragebogen Mastzell-Erkrankungen - Patientenversion

https://www.humangenetics.uni-bonn.de/de/forschung/forschungsprojekte/mastzellerkrankungen/checklistepatientenversion

 

Full List of Publications and Presentations by Lawrence B. Afrin, M.D.

http://mastcellresearch.com/full-list-of-publications-and-presentations-by-lawrence-b-afrin-md/

Dr. Theoharis C. Theoharides

https://www.mastcellmaster.com/

 

The Mastocytosis Society

https://www.tmsforacure.org/